'Love & Other Drugs:' Are Anne & Jake the Hottest Repeat Co-Stars?

Kim Conte

anne hathaway jake gyllenhaalJake Gyllenhaal and Anne Hathaway are hot for each other in the brand-new romantic comedy, Love and Other Drugs, which opens November 24.

If you're having a feeling of deja vu seeing the two together, that's because they've starred together before -- as a married couple in Brokeback Mountain (although their characters weren't so hot for each other that time around).

Obviously, Anne and Jake are far from being the first actors to co-star together more than once. Here are a few of our favorite hottest repeat celebrity co-stars.


Leonardo DiCaprio and Kate Winslet first broke our hearts in Titanic (1997) and then did it all over again in Revolutionary Road (2008).

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Tom Cruise and Cameron Diaz are no strangers to sharing a movie billing more than once -- first in Vanilla Sky (2001) and later in this year's Knight and Day.

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Brad Pitt and Cate Blanchett showed us how intense they can together in Babel (2006) and The Curious Case of Benjamin Button (2008).

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Julia Roberts was Richard Gere's pretty woman not once but twice -- first in Pretty Woman (1990) and then in Runaway Bride (1999).

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Another leading lady who is a good match for Mr. Gere? The gorgeous Diane Lane. The two co-starred in The Cotton Club (1984), Unfaithful (2002), and Nights in Rodanthe (2008).

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Finally, as we saw in Sleepless in Seattle (1993), Joe Versus the Volcano (1990), and You Got Mail (1998), Tom Hanks and Meg Ryan are the classic Hollywood pair.

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Who are your favorite repeat celebrity co-stars?


Image via 20th Century Fox

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